AgingSOS® Hallmarks of Longevity Panel

Advanced Cellular Aging, Cardiovascular & Metabolic Health Assessment

Discover What Your Biology Reveals About Healthy Aging

Aging is more than the passage of time. Changes in cellular metabolism, oxidative stress, inflammation, and cardiovascular health can occur long before noticeable symptoms develop.

The AgingSOS® Hallmarks of Longevity Panel is a comprehensive laboratory assessment featuring 28 biomarkersacross three important areas of health: cellular aging, cardiovascular risk, and metabolic function.

Unlike conventional wellness panels, this assessment combines established clinical biomarkers with specialized markers being investigated for their relationships to cellular aging and longevity.

1. Unique Biomarkers — Cellular Health & Aging

Explore biological processes involved in cellular maintenance, oxidative stress, inflammation, and age-related changes.

• Intracellular NAD⁺ (Nicotinamide Adenine Dinucleotide): An essential coenzyme involved in cellular energy metabolism, mitochondrial function, and DNA repair.
• Klotho Protein: A protein being studied for its associations with aging, kidney function, and cellular resilience.
• Senescence-Associated β-Galactosidase (SAβG): A research marker associated with cellular senescence, a process in which cells enter a state of prolonged growth arrest.
• 8-Hydroxy-2′-Deoxyguanosine (8-OHdG): A biomarker associated with oxidative DNA damage.
• Reactive Oxygen Metabolites (ROM): Indicators of oxidative stress and reactive oxygen metabolite activity.
• Total Antioxidant Capacity (TAC): An assessment of the body’s overall antioxidant capacity.
• Interleukin-1β (IL-1β): An inflammatory signaling protein.
• Interleukin-6 (IL-6): A cytokine involved in immune responses and inflammation.
• Interleukin-8 (IL-8): A chemokine associated with inflammatory cell recruitment.
• Tumor Necrosis Factor-α (TNF-α): A cytokine involved in systemic inflammatory signaling.

2. Cardiovascular Risk Biomarkers

Assess important indicators associated with lipid metabolism, vascular health, and cardiovascular risk.

• LDL Cholesterol: A major marker used in assessing atherosclerotic cardiovascular risk.
• HDL Cholesterol: A component of lipid assessment involved in cholesterol transport.
• Triglycerides: Circulating fats associated with metabolic and cardiovascular health.
• Apolipoprotein B (ApoB): A measure reflecting the number of atherogenic lipoprotein particles.
• Lipoprotein(a) [Lp(a)]: A largely genetically determined cardiovascular risk factor.
• Homocysteine: An amino acid associated with several metabolic pathways and certain cardiovascular risk relationships.
• D-Dimer: A marker of fibrin breakdown, interpreted in specific clinical contexts.

3. Metabolic Health Biomarkers

Evaluate markers associated with glucose regulation and metabolic health.

• Glucose: Measures circulating blood glucose.
• Hemoglobin A1c (HbA1c): Reflects average blood glucose over approximately two to three months.
• Glycated Serum Proteins (GSP): Reflects glycemic exposure over a shorter period than HbA1c.
• Uric Acid: A metabolic marker associated with purine metabolism and several cardiometabolic conditions.

What Makes This Panel Different?

Comprehensive Biomarker Assessment

Combines specialized cellular-aging markers with established cardiovascular and metabolic measurements.

28 Biomarkers Across Multiple Biological Systems

Provides a broad assessment of biological pathways associated with health and aging.

Complimentary Results Consultation

Includes a consultation to help explain laboratory findings and their potential relevance.

Convenient Blood Collection

Mobile blood collection may be available depending on geographic location and service arrangements.

Understand Your Biology. Support Your Healthspan.

The AgingSOS® Hallmarks of Longevity Panel offers an opportunity to explore biological processes that influence cellular function, cardiovascular health, and metabolism.

Measure. Understand. Make Informed Decisions.

Important: Some specialized biomarkers included in this panel remain investigational. The panel is not a validated standalone measurement of biological age, a predictor of lifespan, or a substitute for individualized medical evaluation. The manufacturer advertises 28 biomarkers; the list above describes the 21 individually identified in the supplied product information.